Biotechnology applied to human diseases

Field of study: Biotechnology in Health
Description: Determination of population genetic variations in human diseases. Evaluation of the applicability of biomarkers of prognosis and biological tumor behavior in malignant neoplasias, integrating the basic research to clinical research applied to the resolution of current clinical problems. Use of clinical, laboratory, anatomopathological and imaging resources for the knowledge of the pathophysiological mechanisms and therapeutics of chronic, neoplastic and infectious diseases. Analysis of gene expression, using varied and innovative tools, with the purpose of implementing processes and services that can be applied in the public health system. Biochemical and immunopathological changes due to contact or exposure to chemical and biological agents. The study of this line addresses the use of new technologies, such as high performance sequencing, use of DNA and RNA hybrids probes, immunohistochemistry, flow cytometry, time PCR Real, among others, to investigate genomic, proteomic and metabolomic alterations related to the various clinical manifestations of human diseases.

Abbreviation Titlesort descending Starting date Deadline (months)
10/10/2014 48
24/04/2015 24
Association study of polymorphisms with obesity and type 2 diabetes 01/08/2018 48
SOMA-SI A Well-Being Self-Management Program based on the Stress Analysis of Public Security Agents in Espírito Santo 01/09/2021 48
Blocking of Sestrins, PD-1 and p38 MAP kinase signalling to enhance anti-Leishmania specific immunity in humans 01/07/2018 60
FDBDNF Determining factors for quantitative methylation of the brain-derived neurotrophic factor (BDNF) coding gene in patients using SUS 12/07/2021 12
EPIGNR3C1BDNF Influence of lifestyle on the epigenetic alteration of the glucocorticoid receptor (NR3C1) and brain-derived neurotrophic factor (BDNF) genes 01/08/2020 12
MEMOLD Multidisciplinary study related to possible changes of memory found elderly people from Vitória, ES, Brazil. 04/11/2015 36
The C79G polymorphism of the beta-adrenergic receptor-2 (ADRB2) gene and prediction of asthma risk, response to therapy and interaction with environmental factors in children participating in the AsmaVix project living in areas with monitored air quality 10/12/2019 36
02/11/2010 24
LONGbioPolim 01/08/2013 24
Cannabis ES 01/06/2013 24
NAPiRim 01/03/2009 60
02/01/2013 18
RAMs 09/06/2020 90
Biotcan 01/01/2009 60
01/08/2013 24
18/07/2011 60
01/08/2013 24


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